20.106J/1.084J: Systems Microbiology
Microbiology from a systems perspective.
Prerequisites
5.111, 5.112 or 3.091; 7.012, 7.013, or 7.014
Course Textbook
Madigan, Michael, and John Martinko. Brock Biology of Microorganisms. 11th ed. Upper Saddle River, NJ: Pearson Prentice Hall, 2006. ISBN: 0131443291.
Grading
Grading criteria.
| ACTIVITIES |
PERCENTAGE |
| Problem Sets (~1 every 2 weeks) |
25% |
| Midterm I |
20% |
| Midterm II |
20% |
| Final Exam |
35% |
Calendar
Course calendar.
| Lec # |
TOPICS |
LECTURERS |
KEY DATES |
| 1 |
Early Earth/Microbial Evolution |
Prof. Ed DeLong |
|
| 2 |
Cell Structure/Function |
Prof. Ed DeLong |
Problem set 1 out |
| 3 |
Biological Energy Conservation |
Prof. Ed DeLong |
|
| 4 |
Microbial Growth |
Prof. David Schauer |
Problem set 1 due |
| 5 |
Metabolic Regulation |
Prof. Ed DeLong |
Problem set 2 out |
| 6 |
Virology |
Prof. David Schauer |
|
| 7 |
Information Flow in Biological Systems |
Prof. Ed DeLong |
Problem set 2 due |
|
Midterm I |
|
|
| 8 |
Regulation of Cell Activity |
Prof. Ed DeLong |
Problem set 3 out |
| 9 |
Genetic Exchange in Bacteria |
Prof. Ed DeLong |
|
| 10 |
Experimental Evolution: Optimization of Metabolic Systems |
Guest Lecturer, Prof. Christopher Marx from Harvard |
Problem set 3 due |
| 11 |
Genomics I |
Prof. Ed DeLong |
|
| 12 |
Genomics II |
Prof. Ed DeLong |
Problem set 4 out |
| 13 |
Metabolic Diversity I |
Prof. Ed DeLong |
|
| 14 |
Metabolic Diversity II |
Prof. Ed DeLong |
|
| 15 |
Microbial Ecology |
Prof. Ed DeLong |
Problem set 4 due |
|
Midterm II |
|
|
| 16 |
Microbial Growth Control |
Prof. David Schauer |
Problem set 5 out |
| 17 |
Microbe-host Interactions |
Prof. David Schauer |
|
| 18 |
Immunology I |
Megan McBee |
|
| 19 |
Immunology II |
Megan McBee |
Problem set 5 due |
| 20 |
Diagnostic Microbiology |
Prof. David Schauer |
Problem set 6 out |
| 21 |
Person-to-person Transmission |
Prof. David Schauer |
|
| 22 |
Epidemiology |
Megan McBee |
Problem set 6 due |
| 23 |
Animal- and Arthropod-transmitted Diseases |
Prof. David Schauer |
|
| 24 |
Review |
Prof. David Schauer |
|
|
Final Exam |
|
|